Recently I had to deal with an error that was strange:
The situation was like this: There are many threads in a server application, for each client one, and there are separate threads for special jobs that kind of run in the background. We use distant objects and hence proxies. Usually communication from the server to the client is done from the thread that was created for this client of the proxy we get when the client registers. We use a NSConnection for this purpose and acquire the proxy that the client is offering.
To let our background processes use this proxy I had enableMultipleThreads called in the NSConnection object like the documentation states. But I always got an NSObjectInaccessibleException. Turns out you have to get the NSConnection from the proxy and call enableMultipleThreads there:
...
  NSDistantObject *myProxy = [[myClientConnection rootProxy] retain];
  NSConnection *connection = [myProxy connectionForProxy];
  [connection enableMultipleThreads];
...

Sometimes you forget how old Objective-C really is. Nowadays it is generally considered a bad idea to give a client a pointer (or Object Reference in Java) to an object that belongs solemnly to the client. Usually you would expect a copy - that way the client ensures encapsulation.
But what I often stumbled on is that classes from the framework give back pointers instead. So be careful. Those pointers may only be valid a very short time. As an example:
You have a popup button and you'd like to change the content. But you also want to keep the selected item, in case it is still among the new content. You do something like this:
...
  NSString *selectedTitle = [[myPopupButton selectedItem] title]; // should make a copy here!
  [myPopupButton removeAllItems];
  [myPopupButton addItemsWithTitles: myArrayOfNewTitles];
  [myPopupButton selectItemWithTitle: selectedTitle]; //will crash here because selectedTitle is no longer valid after the removeAllItems call!
...
The same goes for the FieldEditor. You usually need it when you want to check what the user entered in a textfield but without ending text editing. So you call the FieldEditor (only one instance per window) like this:
-(void) controlTextDidChange: (NSNotification*) aNotification
{
  NSTextView *fieldEditor = [[aNotification userInfo] objectForKey: @"NSFieldEditor"];
  NSString *entry = [fieldEditor string]; // if you need this afterwards be sure to make a copy!
  ...
}
So don't be surprised if you get back a pointer that might change or gets invalid. Act safe and make a copy of what you need to be around!